Irish journal of medical science
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Oxysterol binding protein-related protein 9 (ORP9) may be related to the pathogenesis of cerebral infarction since it is closely related with glucose and lipid metabolism. The present study was designed to investigate the genetic relationship between ORP9 gene polymorphisms and cerebral infarction (CI) in Hunan Han population. ⋯ T allele of rs768529 may be a risk factor for the formation of the carotid vulnerable plaque in Chinese Hunan Han population.
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Biography Historical Article
Robert Whytt (1714-1766): from dropsy in the brain to tuberculous meningitis.
Robert Whytt was born and educated in Edinburgh and served the City in the Royal Infirmary. A prolific author, his major work is usually said to be his Essay on the Vital and other Involuntary Movements of Animals (1751), based on his belief that a 'sentient principle' was not limited to the nervous system but was distributed throughout the body, a view that brought him into conflict with Albrecht von Haller, who held that the sentient and motor powers of the body were those of a machine. Whatever about the speculative nature of the sentient principle, Whytt was a clinician blessed with unusual clarity, and he is remembered today for his Observations on the Dropsy in the Brain (1768). ⋯ John Cheyne, in describing two terminal cases, recognised the connexion between hydrocephalus and scrophula, and Dorothy Price provided a precise guide to the clinical picture in 1942. When streptomycin became available Christopher McSweeney used it to alter the bleak picture in Dublin, and was helped by the prevention resulting from neonatal BCG immunisation. Later antimicrobials have facilitated the avoidance of emergent bacillary resistance.
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Letter Case Reports
Isolated hepatic sarcoidosis mimicking liver microabscesses: a case report.
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Self-poisoning accounts for up to 10 % of hospital admissions, some of whom require admission to ICU. Few studies have looked at the epidemiology of these patients in an Irish setting. ⋯ Self-poisoning accounted for 3.8 % of ICU admissions. Patients tend to require a short period of ventilation, with a minority requiring additional organ support. The cost of ICU care is calculated based on previously published methodology to be
7,717 per patient. Extrapolated nationally the annual cost for ICU care for self-poisoning is estimated to be in the order of 5 m. -
To investigate the efficacy of the Ilizarov technique with bone segment extension in tibial infected nonunion. ⋯ The Ilizarov technique with bone segment extension is effective in treating tibial infected nonunion with large bone defects.