The International journal of neuroscience
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Randomized Controlled Trial Comparative Study
Chloral hydrate versus hydroxyzine HCL for sedation prior to pediatric sleep EEG recording.
The sleep electroencephalogram (EEG) can reveal certain epileptiform activity patterns and facilitate localization of the focus. Sedation is often required for sleep EEG recording in pediatric patients, but there is no consensus on the optimal sedative. Hydroxyzine HCL (HH) and chloral hydrate (CH) are popular sedatives, but HH is rarely used for pediatric sleep EEG recording. The goal of this prospective study was to compare CH to HH for sleep induction efficacy, safety and effects on pediatric sleep EEG pattern. ⋯ CH was a superior sedative compared to HH owing to more rapid and successful sleep induction with no increase in adverse events.