Sleep
-
Randomized Controlled Trial Multicenter Study Comparative Study
Evaluation of sham-CPAP as a placebo in CPAP intervention studies.
To evaluate the use of sham-continuous positive airway pressure (CPAP) treatment as a placebo intervention. ⋯ This paper was a secondary analysis of clinical trial data. CATNAP: CPAP Apnea Trial North American Program, the trial from which the data were obtained, is registered with clinicaltrial.gov. Registration #NCT00089752.
-
Randomized Controlled Trial Multicenter Study
A 12-week, randomized, double-blind, placebo-controlled study evaluating the effect of eszopiclone 2 mg on sleep/wake function in older adults with primary and comorbid insomnia.
Longer-term pharmacologic studies for insomnia in older individuals are sparse. ⋯ A Long-Term Safety and Efficacy Study of Eszopiclone in Elderly Subjects With Primary Chronic Insomnia; Registration #NCT00386334; URL - http://www.clinicaltrials.gov/ct2/show/NCT00386334?term=eszopiclone&rank=24
-
Randomized Controlled Trial Comparative Study
Randomized controlled trial of variable-pressure versus fixed-pressure continuous positive airway pressure (CPAP) treatment for patients with obstructive sleep apnea/hypopnea syndrome (OSAHS).
To determine whether fixed-pressure or variable-pressure CPAP was preferred by patients and gave better outcomes in patients with the obstructive sleep apnea/hypopnea syndrome (OSAHS). ⋯ Variable-pressure versus fixed-pressure continuous positive airway pressure (CPAP) treatment for patients with obstructive sleep apnoea/hypopnoea syndrome (OSAHS); Registration # ISRCTN43085025.http://www.controlled-trials.com//SRCTN43085025.
-
Randomized Controlled Trial
Age-related reduction in daytime sleep propensity and nocturnal slow wave sleep.
To investigate whether age-related and experimental reductions in SWS and sleep continuity are associated with increased daytime sleep propensity. ⋯ Healthy aging is associated with a reduction in daytime sleep propensity, sleep continuity, and SWS. In contrast, experimental disruption of SWS leads to an increase in daytime sleep propensity. The age-related decline in SWS and reduction in daytime sleep propensity may reflect a lessening in homeostatic sleep requirement. Healthy older adults without sleep disorders can expect to be less sleepy during the daytime than young adults.