Neurological research

The most recent articles from: February 2015

  • Neurological research · Feb 2015

    Review

    Current evidence of temozolomide and bevacizumab in treatment of gliomas.

    This review article summarizes in vitro, in vivo, and clinical evidence pertaining to temozolomide (TMZ) and bevacizumab (BEV) efficacy and mechanism of action in gliomas. ⋯ Our collected data support the addition of radiotherapy, BEV, and other targeted agents to TMZ treatment, indicating prolonged survival duration in newly diagnosed patients. However, the optimal regimen for treating high-grade glioma cannot be concluded without more clinical trials.

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