Journal of the American Academy of Dermatology

The most recent articles from: J. Am. Acad. Dermatol. July 2015

J. Am. Acad. Dermatol. · Jul 2015

Randomized Controlled Trial Multicenter Study

Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1).

Apremilast works intracellularly to regulate inflammatory mediators. ⋯ Apremilast was effective in moderate to severe plaque psoriasis.

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