The Journal of infection
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The Journal of infection · Feb 2009
Multicenter StudyImpact of inappropriate empirical therapy for sepsis due to health care-associated methicillin-resistant Staphylococcus aureus.
We investigated the influence of empirical therapy on the mortality of patients with health care-associated (HCA) sepsis caused by methicillin-resistant Staphylococcus aureus (MRSA) infections in a multicenter cohort, and the variables associated with inappropriate empirical therapy. ⋯ Inappropriate empirical therapy was independently associated with increased mortality in this multicenter cohort. Clinicians should be aware of the need to consider coverage against MRSA more frequently.