The Journal of infection
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The Journal of infection · Apr 2006
Case ReportsTreatment of prosthetic valve infective endocarditis due to multi-resistant Gram-positive bacteria with linezolid.
Clinical experience with linezolid in the treatment of infective endocarditis either alone or in combination with other agents is limited. We describe our experience in the treatment of two patients with IE due to multi-resistant Gram-positive bacteria. ⋯ Although bacteriostatic, linezolid provides an important therapeutic option in IE due to multi-resistant Gram-positive pathogens. It challenges the conventional wisdom that bactericidal synergy is required for the effective treatment of most cases of IE due to Gram-positive organisms.
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The Journal of infection · Feb 2006
Comparative StudyUse of condoms as blade covers during laryngoscopy, a method to reduce possible cross infection among patients.
Laryngoscope blades are in close contact with mucous membranes and can possibly contaminated with virulent or readily transmissible organisms. As laryngoscopy is often required during endotracheal intubation, proper cleaning and sterilization of the laryngoscope blade is crucial to prevent cross-contamination among patients. ⋯ Condom when using as a blade cover during laryngoscopy is a simple, inexpansive and effective way in reducing cross contamination among patients.
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The Journal of infection · Dec 2005
Review Case ReportsFluconazole treatment of cryptococcal rib osteomyelitis in an HIV-negative man. A case report and review of the literature.
A 49-year-old, HIV-negative publican with single rib cryptococcal osteomyelitis was successfully treated with fluconazole 200mg per day for 10 weeks. This is a case report and a review of the relevant literature.
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The Journal of infection · Dec 2005
Erysipelas and cellulitis: clinical and microbiological spectrum in an Italian tertiary care hospital.
Patients hospitalized in the authors' institution for erysipelas or cellulitis between January 1995 and December 2002 were included in this retrospective review. Two hundred cases of soft tissue infections were hospitalized during the study period. The mean age of the patients was 58 years. ⋯ Soft tissue infections are common and have a high degree of morbidity and require prolonged hospitalization and antibiotic treatment. Microbiological diagnosis is difficult and treatment is based on empiric evidence. ESR and CPR levels on admission may predict the severity of the disease and duration of hospitalization.
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The Journal of infection · Dec 2005
Case ReportsAmikacin and colistin for treatment of Acinetobacter baumannii meningitis.
We report a case of a 52-year-old man with post-surgical meningitis due to a multi-drug resistant Acinetobacter baumannii. Despite therapy with intravenous amikacin and imipenem the meningitis progressed. Upon institution of combination therapy with amikacin by the intravenous and intrathecal (IT) routes, and intravenous colistin the patient experienced successful clinical and microbiological outcomes.