Journal of clinical gastroenterology
-
J. Clin. Gastroenterol. · Mar 2012
Randomized Controlled TrialThe effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial.
The clinical effect of probiotics on irritable bowel syndrome (IBS) is still controversial. ⋯ The probiotic mixture was effective in providing AR of overall IBS symptoms and improvement of stool consistency in D-IBS patients, although it had no significant effect on individual symptoms. The therapeutic effect of probiotics is associated with the stabilization of intestinal microbiota.