Annals of emergency medicine
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Multicenter Study Comparative Study
Serial ECGs are less accurate than serial CK-MB results for emergency department diagnosis of myocardial infarction.
Serial creatine kinase-MB (CK-MB) levels provide more accurate predictive information regarding myocardial infarction than serial ECGs in emergency department patients with chest discomfort and no ST-segment elevation on the initial ECG. ⋯ Serial changes in ECGs during a three- to four-hour interval were associated with the diagnosis of myocardial infarction but were infrequent and less accurate than serial CK-MB levels obtained for the same interval.