Annals of emergency medicine
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Randomized Controlled Trial Clinical Trial
Randomized trial of inhaled flunisolide versus placebo among asthmatic patients discharged from the emergency department.
Inhaled corticosteroids (ICs) improve airflow and decrease symptoms in patients with chronic asthma. We examined whether high-dose inhaled flunisolide would have similar benefits after an emergency department visit for acute asthma. ⋯ Addition of high-dose inhaled flunisolide to standard therapy does not benefit inner-city patients with acute asthma in the first 24 days after ED discharge. Airway inflammation during acute asthma may require higher doses or more potent anti-inflammatory agents.