Annals of emergency medicine
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Randomized Controlled Trial Comparative Study
Sublingual buprenorphine in acute pain management: a double-blind randomized clinical trial.
We compare the efficacy and safety of sublingual buprenorphine versus intravenous morphine sulfate in emergency department adults with acute bone fracture. ⋯ For adults with acute fractures, buprenorphine 0.4 mg sublingually is as effective and safe as morphine 5 mg intravenously.