Annals of emergency medicine
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Review Meta Analysis
Diagnostic accuracy of pulmonary embolism rule-out criteria: a systematic review and meta-analysis.
To perform a systematic review and meta-analysis to define the diagnostic performance of pulmonary embolism rule-out criteria (PERC) in deferring the need for D-dimer testing to rule out pulmonary embolism in the emergency department (ED). ⋯ The existing literature suggests consistently high sensitivity and low but acceptable specificity of the PERC to rule out pulmonary embolism in patients with low pretest probability.