Annals of emergency medicine
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Randomized Controlled Trial Multicenter Study Comparative Study
Randomized Controlled Trial of Intravenous Antivenom Versus Placebo for Latrodectism: The Second Redback Antivenom Evaluation (RAVE-II) Study.
Latrodectism is the most important spider envenomation syndrome worldwide. There remains considerable controversy over antivenom treatment. We aimed to investigate whether antivenom resulted in resolution of pain and systemic effects in patients with latrodectism who received standardized analgesia. ⋯ The addition of antivenom to standardized analgesia in patients with latrodectism did not significantly improve pain or systemic effects.