Annals of emergency medicine
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Randomized Controlled Trial
Rapid Agitation Control With Ketamine in the Emergency Department: A Blinded, Randomized Controlled Trial.
We hypothesized that the use of intramuscular ketamine would result in a clinically relevant shorter time to target sedation. ⋯ In ED patients with severe agitation, intramuscular ketamine provided significantly shorter time to adequate sedation than a combination of intramuscular midazolam and haloperidol.