AJNR. American journal of neuroradiology
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AJNR Am J Neuroradiol · Jun 2007
Differentiation of glioblastoma multiforme and single brain metastasis by peak height and percentage of signal intensity recovery derived from dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging.
Glioblastoma multiforme (GBM) and single brain metastasis (MET) are the 2 most common malignant brain tumors that can appear similar on anatomic imaging but require vastly different treatment strategy. The purpose of our study was to determine whether the peak height and the percentage of signal intensity recovery derived from dynamic susceptibility-weighted contrast-enhanced (DSC) perfusion MR imaging could differentiate GBM and MET. ⋯ The findings of our study show that the peak height and the percentage of signal intensity recovery derived from the Delta R2* curve of DSC perfusion MR imaging can differentiate GBM and MET.
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AJNR Am J Neuroradiol · Jun 2007
Pseudolesions arising from unfolding artifacts in diffusion imaging with use of parallel acquisition: origin and remedies.
Diffusion imaging acquired with echo-planar imaging (EPI) is usually performed with parallel imaging to reduce geometric distortions, especially at high fields. This study reports the occurrence of pseudolesions in EPI with parallel imaging. The unfolding artifacts are attributed as arising from a mismatch between RF sensitivity profiles and distorted acquisition data in the presence of susceptibility effects, plus strong signals on the b=0 images. Examples of pseudolesions from the eyeballs are shown, and remedies are suggested.
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AJNR Am J Neuroradiol · May 2007
Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis.
Subclinical cerebral edema occurs in many, if not most, children with diabetic ketoacidosis (DKA) and may be an indicator of subtle brain injury. Brain ratios of N-acetylaspartate (NAA) to creatine (Cr), measured by proton MR spectroscopy, decrease with neuronal injury or dysfunction. We hypothesized that brain NAA/Cr ratios may be decreased in children in DKA, indicating subtle neuronal injury. ⋯ NAA/Cr ratios are decreased in children during DKA and improve after recovery. This finding suggests that during DKA neuronal function or viability or both are compromised and improve after treatment and recovery.
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AJNR Am J Neuroradiol · May 2007
Case ReportsLightning strike: a rare cause of bilateral ossicular disruption.
Otologic injury associated with fatal and nonfatal lightning strikes has been sporadically reported in the literature. The most common acoustic insult is a conductive hearing loss secondary to rupture of the tympanic membrane. Although conjecture has been made of the theoretic possibility of ossicular injury from lightning strike, to our knowledge, none has been demonstrated intraoperatively or postmortem. We report the first documented case of ossicular disruption in a lightning-strike victim.
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AJNR Am J Neuroradiol · May 2007
Safety and feasibility of intra-arterial nicardipine for the treatment of subarachnoid hemorrhage-associated vasospasm: initial clinical experience with high-dose infusions.
Delayed cerebral ischemia from vasospasm is a major complication after aneurysmal subarachnoid hemorrhage (SAH), but complications and/or low efficacy are associated with current therapy. We report our initial experience with intra-arterial use of a calcium channel blocker, nicardipine. ⋯ In this small series, high-dose intra-arterial nicardipine infusion to treat SAH-associated vasospasm seems to be safe and effective.