AJNR. American journal of neuroradiology
-
AJNR Am J Neuroradiol · May 2007
Controlled Clinical TrialProton MR spectroscopy and MRI-volumetry in mild traumatic brain injury.
More than 85% of brain traumas are classified as "mild"; MR imaging findings are minimal if any and do not correspond to clinical symptoms. Our goal, therefore, was to quantify the global decline of the neuronal marker N-acetylaspartate (NAA), as well as gray (GM) and white matter (WM) atrophy after mild traumatic brain injury (mTBI). ⋯ WBNAA detected neuronal/axonal injury beyond the minimal focal MR-visible lesions in mTBI. Combined with GM atrophy, the findings may provide further, noninvasive insight into the nature and progression of mTBI.
-
AJNR Am J Neuroradiol · May 2007
Clinical TrialCisternography and ventriculography gadopentate dimeglumine-enhanced MR imaging in pediatric patients: preliminary report.
Complex CSF diseases may be underdiagnosed or poorly understood on conventional CT or MR imaging. Although intrathecal CT cisternography with water-soluble iodinated contrast medium has been used, very few studies have dealt with the intrathecal use of gadopentate dimeglumine (Gd-DTPA), though it appears superior to CT. We report our experience with the intrathecal use of Gd-DTPA for MR cisternography and ventriculography in pediatric patients referred for study and treatment of complex CSF-related diseases. ⋯ Our preliminary results showed no side effects and potential useful clinical applications in the evaluation of CNS diseases involving the ventricular system or the subarachnoid space in selected pediatric patients.
-
AJNR Am J Neuroradiol · May 2007
Comparative Study Clinical TrialMR angiography of dural arteriovenous fistulas: diagnosis and follow-up after treatment using a time-resolved 3D contrast-enhanced technique.
Digital subtraction angiography (DSA) is the method of reference for imaging of dural arteriovenous fistula (DAVF). The goal of this study was to analyze the value of different MR images including 3D contrast-enhanced MR angiography (MRA) with a high temporal resolution in diagnostic and follow-up imaging of DAVFs. ⋯ In this study, TR 3D MRA proved reliable in detecting DAVFs and suitable for follow-up imaging. The technique allowed--within limitations--to grade DAVFs. Although 3D TOF MRA can depict signs of DAVFs, its value for follow-up imaging is limited.
-
AJNR Am J Neuroradiol · May 2007
Clinical TrialTime-resolved MR angiography: optimal parallel imaging method.
Time-resolved (TR) MR angiography (MRA) using parallel imaging techniques is proving to have clinical utility for improving MRA spatial and temporal resolution and separating arterial from venous anatomy. The purpose of this study was to evaluate TR MRA of the intracranial vessels at different integrated parallel acquisition technique (IPAT) factors. ⋯ To obtain arterial and venous information in a clinical setting, intracranial TR MRA is best performed with an IPAT factor of 2 with at least 5 mL of contrast.
-
AJNR Am J Neuroradiol · Apr 2007
Comparative StudyPrediction of cerebral hyperperfusion after carotid endarterectomy using cerebral blood volume measured by perfusion-weighted MR imaging compared with single-photon emission CT.
Cerebral hyperperfusion syndrome is a rare but serious complication of carotid revascularization, including carotid endarterectomy (CEA) and carotid stent placement, which can occur in patients with preoperative impairments in cerebral hemodynamics. The purpose of this study was to determine whether preoperative cerebral blood volume (CBV) measured by perfusion-weighted MR imaging (PWI) could identify patients at risk for cerebral hyperperfusion after CEA. ⋯ Measurements of preoperative CBV by PWI might help to identify patients at risk for cerebral hyperperfusion after CEA in the absence of contralateral ICA steno-occlusive disease.