Behavioural brain research
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Randomized Controlled Trial
Effects of 10 Hz and 20 Hz transcranial alternating current stimulation (tACS) on motor functions and motor cortical excitability.
Synchronized oscillatory activity at alpha (8-12 Hz) and beta (13-30 Hz) frequencies plays a key role in motor control. Nevertheless, its exact functional significance has yet to be solved. Transcranial alternating current stimulation (tACS) allows the frequency-specific modulation of ongoing oscillatory activity. ⋯ While 10 Hz effects developed over 30 min after stimulation, 20 Hz tACS effects were found immediately after stimulation. Following 10 Hz tACS these effects were significantly correlated with CSP duration, indicating interference with inhibitory pathways. The present findings suggest differential effects of stimulation frequency on motor behaviour and M1 excitability.