European heart journal
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European heart journal · Mar 2009
Meta AnalysisBlood pressure reduction and renin-angiotensin system inhibition for prevention of congestive heart failure: a meta-analysis.
It is unclear whether prevention of congestive heart failure (CHF) by drugs that inhibit the renin-angiotensin system (RAS) occurs over and beyond the reduction in blood pressure (BP) achieved by these drugs. ⋯ BP reduction is beneficial for the prevention of CHF. Over and beyond BP reduction, the protective effect of ACEIs and ARBs is greater than that of CCBs.