Scandinavian journal of rheumatology
-
Scand. J. Rheumatol. · Jan 2013
Multicenter StudyLong-term outcome of severe alveolar haemorrhage in ANCA-associated vasculitis: a retrospective cohort study.
Alveolar haemorrhage (AH) is a major cause of early death in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). There is a paucity of information regarding the outcomes of AAV patients presenting with severe AH. ⋯ Severe AH was more commonly associated with PR3-ANCA (vs. MPO-ANCA) and strongly correlated with renal vasculitis. Current treatment of severe AH leads to remission but long-term mortality remains high. Concurrent renal failure and older age were associated with higher mortality.