Preventive medicine
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Preventive medicine · Dec 2024
Review Meta AnalysisCancer mortality among solid organ transplant recipients: A systematic review and meta-analysis.
To evaluate the cancer mortality risk among solid organ transplant recipients through a systematic review and meta-analysis. ⋯ Solid organ transplant recipients face significantly higher cancer mortality risks than the general population, highlighting the need for targeted cancer screening and interventions, especially for female solid organ transplant recipients from East Asia.
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Preventive medicine · Dec 2024
ReviewAn atlas on risk factors for gastrointestinal cancers: A systematic review of Mendelian randomization studies.
Gastrointestinal cancers are one of the most frequent cancer types and seriously threaten human life and health. Recent studies attribute the occurrence of gastrointestinal cancers to both genetic and environmental factors, yet the intrinsic etiology remains unclear. Mendelian randomization is a powerful well-established statistical method that is based on genome-wide association study (GWAS) to evaluate the causal relationship between exposures and outcomes. In the present study, we aimed to conduct a systematic review of Mendelian randomization studies investigating any causal risk factors for gastrointestinal cancers. ⋯ Larger, well-designed Mendelian randomization studies are practical in determining the causal status of risk factors for diseases.
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Preventive medicine · Dec 2024
ReviewAn atlas on risk factors for gastrointestinal cancers: A systematic review of Mendelian randomization studies.
Gastrointestinal cancers are one of the most frequent cancer types and seriously threaten human life and health. Recent studies attribute the occurrence of gastrointestinal cancers to both genetic and environmental factors, yet the intrinsic etiology remains unclear. Mendelian randomization is a powerful well-established statistical method that is based on genome-wide association study (GWAS) to evaluate the causal relationship between exposures and outcomes. In the present study, we aimed to conduct a systematic review of Mendelian randomization studies investigating any causal risk factors for gastrointestinal cancers. ⋯ Larger, well-designed Mendelian randomization studies are practical in determining the causal status of risk factors for diseases.
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Preventive medicine · Dec 2024
ReviewSystematic review of the evidence on physical activity prescriptions for youth.
Despite the well-documented benefits of physical activity (PA), globally, only 20 % of youth engage in sufficient PA. Reviews support the benefits of PA prescriptions on promoting adults' PA, but no comparable reviews exist on studies among youth. This systematic review 1) assesses the state of the evidence regarding PA prescriptions from healthcare practitioners on youths' PA; and 2) identifies gaps to inform future research and practice. ⋯ There is insufficient research on healthcare practitioner delivered PA prescriptions to promote youths' PA to determine effectiveness. Future research with objectively measured PA and more diverse youth samples would advance the evidence.
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Preventive medicine · Dec 2024
ReviewSystematic review of the evidence on physical activity prescriptions for youth.
Despite the well-documented benefits of physical activity (PA), globally, only 20 % of youth engage in sufficient PA. Reviews support the benefits of PA prescriptions on promoting adults' PA, but no comparable reviews exist on studies among youth. This systematic review 1) assesses the state of the evidence regarding PA prescriptions from healthcare practitioners on youths' PA; and 2) identifies gaps to inform future research and practice. ⋯ There is insufficient research on healthcare practitioner delivered PA prescriptions to promote youths' PA to determine effectiveness. Future research with objectively measured PA and more diverse youth samples would advance the evidence.