La Revue de médecine interne
-
Seric hyperviscosity syndrome is a medical emergency linked to hyperproteinemia. The clinical diagnosis hinges on a triad of symptoms: mucosal hemorrhages, visual disturbances, and neurological disorders, observed in the most severe cases. ⋯ Laboratory tests predominantly identify the syndrome's etiology, with Waldenström's macroglobulinemia (characterized by a marked IgM peak) being the most common cause, followed by multiple myeloma and cryoglobulinemias. To prevent recurrence, targeted treatment of the underlying cause is implemented following plasma exchange sessions.
-
Review Historical Article
[Update on the diagnosis and management of functional neurological disorders from Jean-Martin Charcot to 2024].
Functional neurological disorders (FND) represent a major clinical challenge, characterized by neurological symptoms without identifiable organic lesions. Since the initial descriptions by Jean-Martin Charcot in the 19th century, the understanding and management of FND have evolved considerably. This review aims to provide an up-to-date overview of current knowledge on the diagnosis and management of FND, integrating recent advances and multidisciplinary therapeutic approaches. ⋯ The management of FND includes a multimodal approach, combining psychotherapy, physical rehabilitation, and targeted pharmacological interventions. The involvement of emerging technologies such as non-invasive brain stimulation and the use of artificial intelligence tools, opens up new perspectives in patient care. Finally, this review addresses the ongoing challenges related to stigma and the training of healthcare professionals, while proposing avenues for improving the quality of care provided to patients with FND.