European journal of radiology
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Randomized Controlled Trial
Percutaneous treatment of non-contained lumbar disc herniation by injection of oxygen-ozone combined with collagenase.
To evaluate the therapeutic results of oxygen-ozone combined collagenase injection for the treatment of lumbar disc herniation compared to the surgery. And to explore the role of this minimally invasive treatment as an alternative to disc surgery. ⋯ The combination of the oxygen-ozone with collagenase shows significant reductions in pain and improvements in function at 3 and 12 months, it can be considered as an option for the treatment of non-contained lumbar disc herniation instead of surgery.