European journal of radiology
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To determine if changes in surrounding tissues of soft-tissue sarcomas (STS) evaluated by MRI during neoadjuvant chemotherapy (NAC) are associated with the histological response and satellite tumorous cells beyond the pseudocapsule on surgical specimen, disease-free survival (DFS) and overall survival (OS). ⋯ Surrounding tissues of STS during NAC should be carefully evaluated as they may steer treatment efficacy and patient prognosis.
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Bronchial thermoplasty (BT) can be considered in the treatment of severe asthma to reduce airway smooth muscle mass and bronchoconstriction. We hypothesized that BT may thus have long-term effects on airway dimensions and air-trapping detectable by quantitative computed tomography (QCT). ⋯ BT significantly reduced airway narrowing and air-trapping in patients with severe asthma. This can be interpreted as direct therapeutic effects caused by a reduction in airway-smooth muscle mass and changes in innervation. A reduction in air-trapping indicates an influence on more peripheral airways not directly treated by the BT procedure.
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To retrospectively assess magnetic resonance imaging (MRI) findings that can predict lymphovascular invasion (LVI) in invasive breast cancer patients who were diagnosed with clinically negative axillary lymph nodes (LNs) preoperatively. ⋯ We found that the tumor ADC value, peritumoral ADC value, and peritumor-tumor ADC ratio were predictive MRI findings for LVI in patients aged ≤55. The tumor ADC value was the most significant predictor for LVI; moreover, inter-observer agreement for the tumor ADC value was substantial between two blinded observers with differences in interpretation experience.
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This study aimed to investigate the predictive ability of magnetic resonance imaging (MRI) based radiomics signature for the preoperative staging in HNSCC. ⋯ Radiomics signature based on MRI could discriminate stage I-II from stage III-IV HNSCC, which may serve as a complementary tool for preoperative staging.
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To investigate the influence of different region of interest (ROI) selection methods on the histogram analysis of apparent diffusion coefficient (ADC) maps and to compare their performance in predicting overall survival (OS) in patients with locally advanced head and neck squamous cell carcinoma (HNSCC). ⋯ ROI selection methods could influence ADC histogram analysis. ADC10 based on ROIWT had the best independent prognostic value for patients with locally advanced HNSCC.