The Journal of asthma : official journal of the Association for the Care of Asthma
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Randomized Controlled Trial
A pilot randomized trial of nebulized amphotericin in patients with allergic bronchopulmonary aspergillosis.
Nebulized amphotericin B (NAB) has been used in the management of acute stage and exacerbations of allergic bronchopulmonary aspergillosis (ABPA). Whether NAB can prevent exacerbations of ABPA is not known. Herein, we evaluate the efficacy and safety of NAB in subjects with ABPA complicating asthma. ⋯ NAB seems to be beneficial in decreasing the frequency of exacerbations in patients with ABPA complicating asthma. Larger trials are required to confirm our study results.