American journal of kidney diseases : the official journal of the National Kidney Foundation
-
Review Meta Analysis
Timing of renal replacement therapy initiation in acute renal failure: a meta-analysis.
Some studies have suggested that early institution of renal replacement therapy (RRT) might be associated with improved outcomes in patients with acute renal failure (ARF). ⋯ This hypothesis-generating meta-analysis suggests that early initiation of RRT in patients with ARF might be associated with improved survival, calling for an adequately powered randomized controlled trial to address this question.
-
Review Meta Analysis
Recovery of kidney function after acute kidney injury in the elderly: a systematic review and meta-analysis.
The prevalence of elderly individuals continues to increase over time, as does the incidence of acute kidney injury (AKI). However, it is not known whether age is an important prognostic predictor for renal recovery after an episode of AKI. ⋯ There is impaired recovery of kidney function after AKI in aged individuals. Future studies should be cognizant of "age" as a potential effect modifier in the prognosis after AKI, and clinical trials should focus on improving outcomes in the elderly cohort.