Pharmacotherapy
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
High-dose versus standard-dose epinephrine treatment of cardiac arrest after failure of standard therapy.
To assess the efficacy of high-dose epinephrine (HDE) compared with standard-dose epinephrine (SDE) in emergency department patients in cardiac arrest after SDE failed to improve asystole or ventricular fibrillation. ⋯ Our results are similar to those of controlled clinical trials comparing HDE with SDE in cardiac arrest.