Pharmacotherapy
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of 6-hour infusion versus bolus furosemide in premature infants.
To compare the renal, hemodynamic, and pulmonary effects of a 6-hour infusion of furosemide versus conventional bolus administration in premature infants. ⋯ Our data suggest that a 6-hour infusion of furosemide does not offer substantial clinical advantage over conventional bolus administration in premature infants when focusing on urine output, blood pressure, FENa, or pulmonary effect.