International journal of cardiology
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Multicenter Study Observational Study
Incidence of bleeding in patients with atrial fibrillation and advanced liver fibrosis on treatment with vitamin K or non-vitamin K antagonist oral anticoagulants.
To investigate the incidence of bleeding events in atrial fibrillation (AF) patients treated with vitamin K (VKAs) or non-vitamin K antagonist oral anticoagulants (NOACs) screened for the presence of liver fibrosis (LF). ⋯ We found a significant association between LF and major bleedings in AF patients treated with VKA, which was not evident in patients on NOACs.