Cephalalgia : an international journal of headache
-
Two randomized, double-blind, sham-controlled trials (ACT1, ACT2) evaluated non-invasive vagus nerve stimulation (nVNS) as acute treatment for cluster headache. We analyzed pooled ACT1/ACT2 data to increase statistical power and gain insight into the differential efficacy of nVNS in episodic and chronic cluster headache. ⋯ nVNS is a well-tolerated and effective acute treatment for episodic cluster headache.