Klinische Pädiatrie
-
Klinische Pädiatrie · Mar 2003
Randomized Controlled Trial Comparative Study Clinical TrialGamma-hydroxybutyrate versus chlorprothixene/phenobarbital sedation in children undergoing MRI studies.
Few clinical studies have assessed gamma-hydroxybutyrate and chlorprothixene/phenobarbital sedation in children. This prospective trial compared the two regimes in children, in particular concerning differences in recovery time. ⋯ Due to its significantly shorter recovery time, gamma-hydroxybutyrate is a reasonable sedative drug for children undergoing non-invasive diagnostic procedures, and is superior to chlorprothixene/phenobarbital. In pediatric oncology patients gamma-hydroxybutyrate appears to be associated more often with vomiting. The long recovery time and its great variability make chlorprothixene/phenobarbital a less valuable alternative.