Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
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J. Oral Maxillofac. Surg. · Nov 2003
Sevoflurane general anesthesia: an alternative technique in the pediatric oral and maxillofacial surgery patient.
The objective of this prospective descriptive study was to report our experience with an alternative general anesthetic technique, using sevoflurane for the pediatric patient, in an ambulatory setting. ⋯ The results of this prospective descriptive study indicate that this technique is an effective and acceptable alternative to other modalities for the control of apprehension and fear in the pediatric patient in an ambulatory oral and maxillofacial facility.
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J. Oral Maxillofac. Surg. · Oct 2003
Interleukin-1beta, interleukin-1 receptor antagonist, and interleukin-1 soluble receptor II in temporomandibular joint synovial fluid from patients with chronic polyarthritides.
The aim of this study was to investigate whether interleukin-1beta (IL-1beta), interleukin-1 receptor antagonist (IL-1ra), or soluble IL-1 receptor II (sIL-1RII) in synovial fluid or plasma is associated with joint pain or signs of tissue destruction in patients with temporomandibular joint (TMJ) involvement of polyarthritides. ⋯ IL-1ra and sIL-1RII are present in different proportions in TMJ synovial fluid and blood plasma from patients with TMJ involvement of polyarthritis. Both of these molecules seem to influence the clinical features of these forms of TMJ inflammation.
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J. Oral Maxillofac. Surg. · Sep 2003
Randomized Controlled Trial Clinical TrialDexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation.
The therapeutic effects of glucocorticoids are generally attributed to suppression of multiple signaling pathways involved in the inflammatory response leading to decreased levels of inflammatory mediators at the site of injury. This study evaluated the in vivo relationship between levels of prostanoids at the site of tissue injury and analgesia after dexamethasone administration in a clinical model of tissue injury. ⋯ The lack of an analgesic effect for dexamethasone while reducing both PGE(2) and TxB(2) at the site of injury in comparison to ketorolac analgesia accompanied by greater reductions in levels of these prostanoids suggests that glucocorticoids at this dose do not suppress PGE(2) release sufficiently to attenuate peripheral sensitization of nociceptors after tissue injury.