Progress in neuro-psychopharmacology & biological psychiatry
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Prog. Neuropsychopharmacol. Biol. Psychiatry · Aug 2013
Meta AnalysisWhite matter deficits in first episode schizophrenia: an activation likelihood estimation meta-analysis.
Diffusion tensor imaging (DTI) has been widely used in psychiatric research and has provided evidence of white matter abnormalities in first episode schizophrenia (FES). The goal of the present meta-analysis was to identify white matter deficits by DTI in FES. ⋯ The current findings provide evidence confirming the lack of connection in the fronto-limbic circuitry at the early stages of the schizophrenia. Because the coordinates reported in the primary literature were highly variable, future investigations with large samples would be required to support the identified white matter changes in FES.
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Prog. Neuropsychopharmacol. Biol. Psychiatry · Aug 2013
Meta AnalysisMeta-analysis: aerobic exercise for the treatment of anxiety disorders.
This meta-analysis investigates the efficacy of exercise as a treatment for DSM-IV diagnosed anxiety disorders. ⋯ Current evidence does not support the use of aerobic exercise as an effective treatment for anxiety disorders as compared to the control conditions. This remains true when controlling for length of exercise sessions and type of anxiety disorder. Future studies evaluating the efficacy of aerobic exercise should employ larger sample sizes and utilize comparison interventions that control for exercise time.