Progress in neuro-psychopharmacology & biological psychiatry
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Prog. Neuropsychopharmacol. Biol. Psychiatry · Jul 2020
Review Meta AnalysisNoninvasive brain stimulation in alcohol craving: A systematic review and meta-analysis.
Alcohol dependence (AD) is characterized by a set of physical and behavioral symptoms, which may include withdrawal, tolerance and craving. Recently, noninvasive brain stimulation (NIBS) methods, namely transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), have been investigated as possible new therapeutic approaches for adjusting the pathological neuroplasticity involved in alcohol dependence. Therefore, we conducted a systematic review and meta-analysis on the therapeutic uses of tDCS and rTMS in AD patients. ⋯ There is no evidence for a positive effect of tDCS/rTMS on various dimensions of AD. We need more randomized, double blind, sham controlled trials with enough follow-up periods to evaluate the efficacy of tDCS/rTMS for alcohol dependence treatment.
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Prog. Neuropsychopharmacol. Biol. Psychiatry · Jul 2020
Review Meta AnalysisNoninvasive brain stimulation in alcohol craving: A systematic review and meta-analysis.
Alcohol dependence (AD) is characterized by a set of physical and behavioral symptoms, which may include withdrawal, tolerance and craving. Recently, noninvasive brain stimulation (NIBS) methods, namely transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), have been investigated as possible new therapeutic approaches for adjusting the pathological neuroplasticity involved in alcohol dependence. Therefore, we conducted a systematic review and meta-analysis on the therapeutic uses of tDCS and rTMS in AD patients. ⋯ There is no evidence for a positive effect of tDCS/rTMS on various dimensions of AD. We need more randomized, double blind, sham controlled trials with enough follow-up periods to evaluate the efficacy of tDCS/rTMS for alcohol dependence treatment.