Thrombosis research
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Thrombosis research · Jun 2013
Randomized Controlled TrialDecreased platelet miR-223 expression is associated with high on-clopidogrel platelet reactivity.
We aimed to investigate the relationship between platelet microRNA (miR-223 and miR-96) expression and clopidogrel responsiveness in patients with coronary heart disease (CHD). ⋯ The present work identifies decreased platelet miR-223 expression as a novel mechanism involved in blunted platelet response to clopidogrel in a Chinese population.