Annales françaises d'anesthèsie et de rèanimation
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Ann Fr Anesth Reanim · Jan 2003
Randomized Controlled Trial Comparative Study Clinical Trial[Effects of equiosmolar load of 20% mannitol, 7.5% saline and 0.9% saline on plasma osmolarity, haemodynamics and plasma concentrations of electrolytes].
Mannitol 20% (M) and NaCl 7.5% (H) are hypertonic solutions used in-patient in hypovolaemic shock and in case of increased ICP. To our knowledge no study in humans compared them in an equiosmolar load. The objectives of this study were to compare the pharmacokinetics of both solutions in an equiosmolar load with an isotonic solution (NaCl 0.9% (C)) in terms of osmolarity, electrolytes and haemodynamic parameters over time. ⋯ A single infusion of 4.95 mOsm kg(-1) of mannitol 20% or NaCl 7.5% induces a similar osmolar variation over time with a maximal effect after 10 min.
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Data synthesis on physiopathology and treatment of hepatorenal syndrome (HRS). ⋯ Prognosis of patients with HRS remains poor but the pharmacologic treatment by terlipressine has improved the prognosis particularly in order to wait liver transplantation.
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Ann Fr Anesth Reanim · Jan 2003
Case Reports[Allergy investigations after two cases of adverse reactions to a neuromuscular blocking agent and management for subsequent general anaesthesia].
We report two cases of severe anaphylactic reactions to rocuronium. Diagnosis was confirmed by skin tests and specific IgE assay. ⋯ Intradermal tests and leukocyte histamine release were negative for cisatracurium. The two patients had undergone a subsequent general anaesthesia using cisatracurium and did not present any adverse reaction.
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Ann Fr Anesth Reanim · Jan 2003
[The impact of a French guideline on the clinical management of severe head injury (SHI) published in 1999].
To evaluate the impact of a French guideline on the clinical management of severe head injury (SHI) published in 1999. ⋯ The French guidelines had a significant impact and seem to have provided a useful aid to clinical management of SHI patients. ICP monitoring and the shortage in post-ICU facilities are remaining issues.