Annales françaises d'anesthèsie et de rèanimation
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Ann Fr Anesth Reanim · Aug 2004
Review[Laboratory animal anaesthesia: influence of anaesthetic protocols on experimental models].
The use of experimental animals requires anaesthesia to provide immobility and analgesia. Animals require anaesthesia not only for ethical reasons but also because pain and stress can alter the quality of research results. Recognition of pain, and its treatment is important throughout the procedure. ⋯ The same anaesthetic could have opposite effects from an organ to another. For results validation, the anaesthesia side effects (hypoventilation, hypotension, cooling em leader ) have to be minimized. All new experimental models should require discussing the possible interferences between anaesthesia and results and to compare results obtained with different anaesthetic protocols.