Annales françaises d'anesthèsie et de rèanimation
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Ann Fr Anesth Reanim · Oct 2012
Randomized Controlled Trial Comparative Study[Storage at room temperature does not change cisatracurium onset time: a prospective, randomized, double-blind controlled study].
Storage of cisatracurium at room temperature seems to have no effect on its degradation in vitro contrary to the recommendations of storage at +4°C. The purpose of this study was to evaluate the influence of cisatracurium' s storage temperature on its onset time. ⋯ This study demonstrated that cisatracurium's storage at room temperature had no influence on its onset time. It provides an argument for the preservation of cisatracurium at room temperature for a period not exceeding 21 days. Monitoring the onset of curarization may increase the quality score of intubation.
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Ann Fr Anesth Reanim · Oct 2012
Randomized Controlled TrialEffects of a single 1200-mg preoperative dose of gabapentin on anxiety and memory.
Gabapentin has antihyperalgesic and potential anxiolytic effects. We therefore evaluated the effects of gabapentin premedication on anxiety, amnesia, and sedation. We tested the primary hypothesis that 1200mg of oral gabapentin 2 to 3h before surgery reduces preoperative anxiety. Our secondary hypothesis was that gabapentin administration is sedative without causing preoperative amnesia. ⋯ Gabapentin premedication, 1200mg, provided preoperative anxiolysis without causing sedation or impairing preoperative memory.