Annales françaises d'anesthèsie et de rèanimation
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Ann Fr Anesth Reanim · Sep 2013
Randomized Controlled TrialAn effective dose of ketamine for eliminating pain during injection of propofol: A dose response study.
Ketamine can completely eliminate pain associated with propofol injection. However, the effective dose of ketamine to eliminate propofol injection pain has not been determined. The purpose of this study was to determine the effective dose of ketamine needed to eliminate pain in 50% and 95% of patients (ED50 and ED95, respectively) during propofol injections. ⋯ Ketamine at an approximate dose of 0.3mg/kg was effective in eliminating pain during propofol injection.
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Ann Fr Anesth Reanim · Sep 2013
Randomized Controlled Trial[Influence of pressure- and volume-controlled ventilation on pulse pressure variations: Randomized study.]
Pulse pressure variation (ΔPP) has been demonstrated to be an accurate dynamic parameter to predict fluid responsiveness. However, the impact of different ventilator modes on this parameter is unknown. We compared ΔPP values calculated alternatively during pressure- and volume-controlled ventilation. ⋯ ΔPP values obtained with both ventilator modes were not interchangeable. On average, ΔPP decreases by more than two points in the passage VVC to VPC for a given patient, all others things being equal.