Brain and cognition
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Brain and cognition · Dec 2016
ReviewFunctions of the anterior insula in taste, autonomic, and related functions.
The anterior insula contains the primary taste cortex, in which neurons in primates respond to different combinations providing a distributed representation of different prototypical tastes, oral texture including fat texture, and oral temperature. These taste neurons do not represent food reward value, in that feeding to satiety does not reduce their responses to zero, in contrast to the next stage of processing, the orbitofrontal cortex, where food reward value is represented. Corresponding results are found with fMRI in humans. ⋯ More posteriorly in the insula, there is an oral somatosensory region, and posterior to this somatosensory regions that respond to touch to the body. These taste and somatosensory representations in the insula provide representations that are about the external world (touch), are intermediate (oral taste and texture), and are about internal signals related to visceral and autonomic function. This functionality needs to be taken into account when considering activations of the insula found in cognitive tasks.