Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Oct 1995
Randomized Controlled Trial Multicenter Study Clinical TrialAngioplasty of complex lesions in ischemic rest angina: results of the Thrombolysis and Angioplasty in Unstable Angina (TAUSA) trial.
This study sought to analyze the role of complex lesion morphology on the acute results of angioplasty. ⋯ Complex lesions before coronary angioplasty increase acute complication rates after coronary angioplasty. Urokinase as administered in the TAUSA trial had significant adverse effects, especially in complex lesions. However, even in the placebo arm, complex lesions were associated with higher complication rates than simple lesions. Newer antithrombotic measures that particularly target the platelet may eventually decrease complication rates in these lesions.