Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Jul 1996
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialEfficacy of intravenous ibutilide for rapid termination of atrial fibrillation and atrial flutter: a dose-response study.
Currently available antiarrhythmic drugs have limited efficacy for short-term, rapid termination of atrial fibrillation and atrial flutter. ⋯ These data demonstrate that ibutilide is able to rapidly terminate atrial fibrillation and atrial flutter.
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J. Am. Coll. Cardiol. · Jul 1996
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialPrognostic significance of transient ischemic episodes: response to treatment shows improved prognosis. Results of the Total Ischemic Burden Bisoprolol Study (TIBBs) follow-up.
The Total Ischemic Burden Bisoprolol Study (TIBBS) follow-up examined cardiac event rates in relation to transient ischemia and its treatment. ⋯ In patients with stable angina pectoris, frequent episodes of transient ischemia are a marker for an increased event rate. A 100% response to medical treatment reduces the event rate. The greater reduction of ischemia with bisoprolol than nifedipine during the TIBBS trial translated into an improved outcome at 1 year.