Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Oct 2002
Randomized Controlled Trial Comparative Study Clinical TrialBeta-blocker therapy influences the hemodynamic response to inotropic agents in patients with heart failure: a randomized comparison of dobutamine and enoximone before and after chronic treatment with metoprolol or carvedilol.
We compared the hemodynamic effects of dobutamine and enoximone administration before and after long-term beta-blocker therapy with metoprolol or carvedilol in patients with chronic heart failure (HF). ⋯ In contrast with its effects on enoximone, carvedilol and, to a lesser extent, metoprolol treatment may significantly inhibit the favorable hemodynamic response to dobutamine. No such beta-blocker-related attenuation of hemodynamic effects occurs with enoximone.
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J. Am. Coll. Cardiol. · Oct 2002
Randomized Controlled Trial Comparative Study Clinical TrialCost/utility ratio in chronic heart failure: comparison between heart failure management program delivered by day-hospital and usual care.
This study compared the effectiveness and cost/utility ratio between a heart failure (HF) management program delivered by day-hospital (DH) and usual care in chronic heart failure (CHF) outpatients. ⋯ A heart failure outpatient management program delivered by a DH can reduce mortality and morbidity of CHF patients. This management strategy is cost-effective and has an equitable value from a societal point of view.