Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Jun 2003
Randomized Controlled Trial Multicenter Study Clinical TrialBeraprost therapy for pulmonary arterial hypertension.
The purpose of this study was to assess the safety and efficacy of the oral prostacyclin analogue beraprost sodium during a 12-month double-blind, randomized, placebo-controlled trial in patients with pulmonary arterial hypertension (PAH). ⋯ These data suggest that beneficial effects may occur during early phases of treatment with beraprost in WHO functional class II or III patients but that this effect attenuates with time.