Journal of the American College of Cardiology
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J. Am. Coll. Cardiol. · Sep 2012
Meta AnalysisDo changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension? A meta-analysis of 22 randomized trials.
The objectives of this study were to verify whether improvement in 6-min walk distance (6MWD) is associated with clinical outcome in pulmonary arterial hypertension (PAH). ⋯ In patients with PAH, improvement in 6MWD does not reflect benefit in clinical outcomes.