Journal of the American College of Cardiology
-
J. Am. Coll. Cardiol. · Mar 2013
Meta AnalysisCost-effectiveness of statins for primary cardiovascular prevention in chronic kidney disease.
The authors sought to evaluate the cost-effectiveness of statins for primary prevention of myocardial infarction (MI) and stroke in patients with chronic kidney disease (CKD). ⋯ Although statins reduce absolute CVD risk in patients with CKD, the increased risk of rhabdomyolysis, and competing risks associated with progressive CKD, partly offset these gains. Low-cost generic statins appear cost-effective for primary prevention of CVD in patients with mild-to-moderate CKD and hypertension.