Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Randomized Controlled Trial Comparative Study Clinical Trial
Morphine versus methadone in the pain treatment of advanced-cancer patients followed up at home.
The aim of this study was to evaluate the analgesic and adverse effects and the doses of methadone in comparison to morphine. ⋯ Methadone is a drug of indisputable value in the treatment of cancer pain, and an unbalanced focus on the risks of inappropriate use rather than the benefits should not compromise the use of a relevant alternative to morphine in the management of cancer pain.