Journal of neuro-oncology
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Journal of neuro-oncology · Jan 2008
ReviewNew prospects for management and treatment of inoperable and recurrent skull base meningiomas.
Skull base, including optic nerve, cavernous sinus, clival and foramen magnum tumors represent a major challenge for neurosurgeons and neuro-oncologists. Growth regulatory signaling pathways for these tumors are of increasing interest as potential targets for new chemotherapy. ⋯ This article reviews some recent findings pathways that appear to regulate meningioma growth. Potential targets for novel therapies are also discussed.