Clinical nutrition : official journal of the European Society of Parenteral and Enteral Nutrition
-
Review Meta Analysis
Does intravenous fish oil benefit patients post-surgery? A meta-analysis of randomised controlled trials.
Supplementation of fish oil (FO) containing lipid emulsions has been associated with a reduction in the length of hospital stay, infections and liver dysfunction in patients undergoing major surgery. We carried out a meta-analysis and subgroup analysis to examine randomised clinical trial (RCT)-based evidence of the aforementioned effects. ⋯ FO-enriched lipid emulsions are likely to reduce infections, the length of hospital stay and liver dysfunction without influencing mortality and may be a safe and preferable choice in post-surgery patients. Further well-designed trials should be performed to determine whether FO lipid emulsions reduce mortality in patients undergoing hepatic surgery, especially liver transplantation, and the cost effectiveness of such treatment.
-
Review Meta Analysis
The presence and effect of bias in trials of early enteral nutrition in critical care.
Randomized trials suggest that early enteral nutrition is beneficial in critically ill adults. However, methodologic bias can overestimate benefit. ⋯ The benefits attributed to early enteral nutrition were either seen only in trials with high risks of bias or may result from residual risks of bias.