The American journal of emergency medicine
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Case Reports
Extrapontine myelinolysis after correction of hyponatremia presenting as generalized tonic seizures.
Central pontine myelinolysis and extrapontine myelinolysis are rare complications of rapid correction of chronic hyponatremia. Central pontine myelinolysis is more common and more predictable in presentation. ⋯ His presenting sign, generalized seizures, has not been previously reported. We summarize risk factors for myelinolysis, which may be more common than previously thought, as well as steps to minimize risk while managing vulnerable patients.