The American journal of emergency medicine
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Activation of autophagy improved the neurologic outcome after cardiopulmonary resuscitation in rats.
Recent studies have shown the existence of autophagy in cerebral ischemia; however, there has been no research on the role of autophagy in cerebral injury after cardiopulmonary resuscitation (CPR). This study was conducted to determine the role of autophagy in an animal model of ventricular fibrillation (VF)/CPR. ⋯ The activation of autophagy after ROSC offered a remarkable tolerance to VF/CPR ischemic insult and improved the neurologic outcomes.
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Electrocardiography (ECG) offers some information that may be used to prognosticate acute type A aortic dissection (AAOD) for short- and long-term mortality. ⋯ Acute ischemic ECG changes are common in AAOD, and a completely normal ECG is infrequently encountered. Acute ECG changes were not associated with the increased troponin or the presence of coronary lesions in angiography.
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Surfing is a popular recreational and competitive sport in the United States and worldwide. Previous studies indicate surfers are frequently injured, but most studies are survey based, and little is known about surfing injuries that present to emergency departments (EDs). ⋯ Surfing injuries are common but rarely serious. The injuries most commonly affect the lower extremity, head, neck, and face and are most frequently lacerations. Age older than 60 years, injuries to the trunk, and internal organ injuries were associated with a statistically significant increased frequency of hospital admission.
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The purpose of the present study was to investigate the diagnostic value of lactate for predicting bacteremia in female patients with acute pyelonephritis (APN). ⋯ The initial serum lactate level showed poor discriminative performance for predicting bacteremia in female patients with APN.